Meeting 6th May 2020
 

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compbio.dagprojects:meetings20200506 [2020/05/06 13:32] (current)
jabbott created
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 +== Meeting 6th May 2020 ==
 +
 +Present: Marek, William, James
 +
 +=== Marek ===
 +
 +Caroline: Add some additional tables 
 +
 +Tom Snelling: Decoding data has been problematic especially parsing modifications
 +
 +SUMOylation project: RNA-Seq done, alternative splicing analysis using RATS - seem to be ~100 genes differentially spliced. Noisy and probably not anything significant. ATAC-Seq data in different format to previous, so now ready to combine with the rest.
 +
 +=== William ===
 +
 +EDC variants: Rerun with bugfixed GATK and vep to compare with PCR LOF calls. HRNR LOF which looked odd (all homozygotes, departed from Hardy-Weinberg) is now not present. Now formatting in way that can be read into excel in a vcf-like style, including database ID and consequence. 
 +
 +=== James ===
 +
 +NSW: Talked Margarita through using annotation transfer scripts
 +
 +DB: Metagenomics classifiers fail to identify source of reads from enriched GO slims. Instead built a monster bwa database of 8088 taxonomically non-redundant genomes and aligning against this. At least seems to be hitting things...Also now started looking at enrichment analysis of full set of GO terms relating to top 5 enriched SLIMs.
  
 
compbio.dagprojects/meetings20200506.txt · Last modified: 2020/05/06 13:32 by jabbott
 
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