Meeting 15th July 2020
 

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compbio.dagprojects:meetings20200715 [2020/07/15 14:27] (current)
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 +=== Meeting 15th July 2020 ===
 +
 +Present: Marek, WIlliam, James
 +
 +== Marek ==
 +
 +Sumolyation creeping onwards...more hervs and figures, finding overlaps between hervs and IPS chip-seq peaks.
 +
 +HipSci - meeting with Jason, and they seem quite pleased so far. Working through some suggestions - polynomials...first four orders seem to influence things most.
 +
 +Miratul - spent about a day on preliminary analysis. Limitations in databases. Particaularly interested in sub-compartments, but this sub-organelle location not available at present but will come in next release. E2/E5 not showing much. Probably will be two days overall.
 +
 +== William ==
 +
 +SPRR3 deletion not being detected. Looking into why...Chris' binning algorithm not ideal but hadn't wanted to fiddle with this and having to redo everything. Improving this may offer better resolution. Chris used different methods for larger bins. Tried method with granges coverage binning but didn't offer much improvement.
 +
 +Back to the paper, heatmaps of genotype correlation and linkage. 
 +
 +== James ==
 +
 +EDC - investigating SPRR3 problem. Coverage looks to be highly variable due to mapping issues. Reanalysed with deepvariant which seems to be doing a better job.
 +
 +Davide: Improving ASV pipeline to cache obects as created to allow rerunning without having to repeat all analysis. Running on JH03 library currently
 +
 +Metagenomes - counting reads mapped to different cDNAs where GO Terms are common. Close to completing second round analysis
  
 
compbio.dagprojects/meetings20200715.txt · Last modified: 2020/07/15 14:27 by jabbott
 
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